摘要
目的:研究复方西红花膏对损伤组织成纤维细胞凋亡的影响,探讨其促进损伤组织修复的作用机理。方法:采用打击造模的方法,将60只Wistar大白鼠造成急性软组织损伤模型。随机将造模后动物分为空白对照组;阳性药物(万花油)对照组;复方西红花膏治疗组。观察用药2天、4天、7天、10天时成纤维细胞凋亡的变化。结果:复方西红花膏组损伤组织成纤维细胞凋亡呈阳性表达,且复方西红花膏组成纤维细胞凋亡阳性表达下降比其它两组缓慢。结论:复方西红花膏通过促进成纤维细胞凋亡来加速损伤组织修复。
Objective：To study the effect of FFXHHG to the fibroblast apoptosis in wounded tissue in order to elucidate the mechanism of FFXHHG promote the rehabilitation of the wounded tissue. Methods：According to the method of building models by beating, sixty wistar mouse got acute soft tissue＇s lesion. Then they were divided randomly into three groups： group A, used nothing; group B, healed with positive pharmaceutical; group C, coped with FFXHHG. Both group A and group B were control groups, while group C was experimental group. The change of the fibroblast apoptosis was observed respectively at 2, 4, 7 and 10 days since the mouse were dealt with pharmaceutical. Results：The fibroblast apoptosis in wounded tissue was expressed positively in FFXHHG, while the level in FFXHHG decreased more slowly than the other two. Conclusions：FFXHHG could accelerate the rehabilitation of the wounded tissue by promoting the fibroblast apoptosis.
出处
《中国中医骨伤科杂志》
CAS
2006年第3期26-29,共4页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词
复方西红花膏
创伤愈合
急性软组织损伤
成纤维细胞
凋亡
Fu Fang Xi Hong Hua Gao（FFXHHG） Wound healing Acute soft tissue lesion Fibroblast apoptosis
