摘要
[目的]探讨充血性心力衰竭(congestion heart failure,CHF)与免疫功能变化情况。[方法]测定了53例 CHF患儿及50例健康儿童T淋巴细胞亚群、T淋巴细胞转化率、免疫球蛋白及补体(C3)作分析比较。[结果]CHF组 CD3、CD4、CD8、CD4／CD8、T淋巴细胞转化率均显著降低,而IgG、C3升高。[结论]CHF影响患儿免疫功能,并可激活补体系统,造成免疫损伤,加重心功能不全。
[Objective] To learn the change of immune ability under congestion heart failure（CHF）. [Method] 53 CHF and 50 generally healthy children were analyzed and compared on T-lymphocyte subgroup, T-lymphocyte alteration rate, immunoglobulin and complement（Ca ）. [Result] The concentration of CD2 ,CD4 ,CD8 ,CD4/CD8 and T-lymphocyte alteration rate of CHF children were obviously decreased, while IgO and Ca increased. [Conclusion] CHF could weaken the immune ability of children and activate the complement system, thus worsen the heart failure by immune damage.
出处
《中国儿童保健杂志》
CAS
2006年第3期298-299,共2页
Chinese Journal of Child Health Care
