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窒息早产儿凝血因子水平及其对维生素K的治疗反应观察 被引量:8

Blood coagulation factor of asphyxia preterm infant and comprison of prior and post treatment with vitamin K
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摘要 [目的]了解窒息早产儿凝血因子的水平,并通过对维生素K治疗前后凝血因子水平的比较,研究对窒息早产儿预防性应用维生素K的意义。[方法]对10例无窒息等并发症的早产儿和23例早产窒息儿的凝血因子水平进行检测。[结果]窒息组早产儿凝血因子水平比无窒息组早产儿凝血因子水平明显减低(P<0.05),窒息组早产儿治疗前后凝血因子FII、 FIX、FX水平比较差异有显著性(P均<0.05),而FVII治疗前后差异无显著性(P>0.05)。[结论]窒息早产儿组凝血因子明显比无窒息早产儿组低,窒息早产儿生后即给予维生素K治疗对预防出血有意义。 [Objective] To investigate the blood coagulation factor of asphyxia and to investigate the signification of the treatment to asphyxia preterm infant with vitamin K. [Method] The blood coagulation factor of 10 preterm infants without asphyxia and 23 preterm infants with asphyxia were detected. [Results] The blood coagulation factor of asphyxia group decreased obviously when compared with the group without asphyxia(P〈0.05), the FII,FIX,FX of asphyxia group increased obviously after treatment with vitamin K,but FVII had an obvious difference(P〉0.05). [Conclusion] The blood coagulation factor of asphyxia preterm infant decred obviously, obviously compared with the group without asphyxia,was significant and Using vitamin K to asphyxia preterm infant.
作者 毕玫荣 张岩
出处 《中国儿童保健杂志》 CAS 2006年第3期244-245,共2页 Chinese Journal of Child Health Care
关键词 窒息早产儿 凝血因子 维生素K asphyxia preterm infant coagulation faetor vitamin K
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参考文献5

  • 1MICHAEL D,WILLIAMS,STEELHOUSE L.The investigation and management of neonateal haemostasis and thrombosis[J].British Jonurnal of Haematology,2002,119:295-309.
  • 2ELISABETH AL,ANNIE P,JONVILE B.Vitamin K in neonates[J].Peadiatr Drugs,2003,3:1-8.
  • 3SALONVAARA M,RIIKONEN P,KEKOMAKI R,et al.Effects of gestational age and prenatal and perinatal events on the coagulation status in premature infants[J].Archives of Disease in Childhood.Fetal and Neonatal Edition,2003,88:319-321.
  • 4ZIPURSKY,ALVIN,ZIPURSKY,et al.Prevention of vitamin K deficiency bleeding in newborns[J].British Journal of Haematology,1999,104:430-437.
  • 5ARTEAGA V M,ESPINOZA HM,TORRES GE,et al.Effect of oral and intramuscular vitamin Kon the factors Ⅱ,Ⅶ,Ⅸ,Ⅹ,and PIVKA Ⅱ in the in the infant newborn under 60 days of age[J].Revista Medica de Chile,2001,129:1121-1129.

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