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旋转式伽玛刀治疗56例脑转移瘤影像对比与临床疗效分析 被引量:2

Clinical efficacy of rotary gamma-knife radio-surgery in the treatment of 56 patients with brain metastases by imaging comparison
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摘要 目的:探讨MASEP-SRRS伽玛刀治疗脑转移瘤的疗效.方法:56例脑转移瘤采用MASEP-SRRS伽玛刀治疗、Gamma-plan计划系统规划治疗,边缘剂量18~25Gy,平均20Gy,靶点中心剂量32~60Gy,靶点数3~9个,平均5个,随访时间3~32个月.结果:获得随访52例,治疗有效率92.3%(48例),消失53.8%(28例),缩小并强化程度减弱15.4%(8例),转移瘤大小不变但中间出现坏死23%(12例),未出现严重并发症.结论:旋转式伽玛刀治疗脑转移瘤安全、有效. Objective: To estimate the efficacy of rotary gamma-knife radio-surgery in the treatment of brain metastases, Methods: Fifty six patients with brain metastases were treated by MASEP-SRRS rotary gamma-knife, and were followed from 3 months to 32 months. Each of the cases had 5 targets on average (3 to 9). The dosage in the edge of the target were 18 to 25 Gy (mean= 20 Gy), that in the centre were 32 to 60 Gy. Results:Fifty two patients were followed up, which of effective rate were 92.3%(48 cases). The tumor body disappeared in 53.8% of all cases (28 cases), strengthen and extent diminishing in 15.4% (8 cases), had no change but taken place necrosis in the center in 23% (12 cases). There were no serious complications. Conclusion: Gamma knife radio-surgery in the treatment of brain metastases was effective and safe.
出处 《医学影像学杂志》 2006年第5期446-448,共3页 Journal of Medical Imaging
关键词 脑转移瘤 立体定向放射治疗 伽玛刀 Brain metastases tumor Stereotaxic radiotherapy Gamma knife
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