摘要
以糠胺及丙烯腈为原料,通过亲核加成、氢化反应合成了标题化合物,并通过多种谱学手段表征确证。在优化条件下,产物的总收率为75%,含量98%(HPLC)。该化合物对受试革兰氏阴性菌、阳性菌皆有明显的抑制作用。
A new arylamine compound N-（3-aminopropyl） furfuryl amine was synthesized by addition and hydrogenation reactions of furfuryl amine with acrylonitrile. The structure of the title compound was confirmed by spectral characterization. By optimization, the yield and purity reached to 75 % and 98 %, respectively. The compound was found to be active against the five test bacterial organisms.
出处
《化学试剂》
CAS
CSCD
北大核心
2006年第4期239-240,共2页
Chemical Reagents
基金
江苏省普通高校高新技术产业发展项目(JHB05-51)资助
关键词
N-(3-氨基丙基)糠胺
亲核加成
催化加氢
抑菌性
N-（3-aminopropyl） furfuryl amine
nucleophilic addition
hydrogenation
antimicrobial activity
