摘要
目的探讨血浆血管性血友病因子(vWF)、血栓素B(2TXB2)、6-Keto-PGF1α水平与冠心病中医证型的关系。方法应用酶联免疫吸附法(ELISA)、放免法分别测定173例冠心病和31名健康对照者血浆vWF、TXB2、6-Keto-PGF1α的水平,并对不同证型的冠心病患者的指标进行比较。结果与正常对照组比较,冠心病组vWF、TXB2水平显著增高(P<0.05),血浆6-keto-PGF1α水平较对照组明显降低(P<0.05)。且心血瘀阻、痰阻心脉证型血浆vWF、TXB2、6-keto-PGF1α水平均高于心肾阴虚、气阴两虚证型(P<0.05,P<0.01)。结论血浆VWF、TXB2、6-keto-PGF1α水平与冠心病中医辨证分型有一定的相关性。
Objective To investigate the correlation between plasma yon Willebrand factor （vWF）,TXB2,6-Keto-PGF1α and differential traditional Chinese medicine （TCM）syndromes of coronary heart disease （CHD）. Methods In 173 patients with coronary heart disease and 31 healthy people, the plasma vWF was measured by ELISA, and the plasma TXB2 and 6-Keto-PGF1α were measured by radio immunoassay. Results Compared with healthy people, the levels of plasma vWF and TXB2 were significantly higher in CHD patients （P〈 0.05）;the levels of plasma 6-Keto-PGF1α was significantly lower in CHD patients （P〈 0.05）;the levels of plasma vWF,TXB2,6-Keto-PGF1α of cardiac blood stasis group,phlegm retention in heart vessel group were significantly higher than those of deficiency of both heart-yin and kidney-yin group and asthenia of both qi and yin group（P 〈 0.05）. Conclusion There are correlations between plasma vWF,TXB2,6-Keto-PGF1α and differential TCM syndromes in coronary heart disease（CHD）.
出处
《上海中医药杂志》
北大核心
2006年第6期13-14,共2页
Shanghai Journal of Traditional Chinese Medicine
