摘要
目的:探讨心脏停搏患者心肺复苏自主循环恢复后高丙氨酸转氨酶血症的临床意义。方法:对33例心肺复苏患者高丙氨酸转氨酶血症情况进行系统观察。结果:心肺复苏患者中有81.8%(27/33)的患者存在高丙氨酸转氨酶血症现象(血清丙氨酸转氨酶活力40￣249U/L),其中血清丙氨酸转氨酶>40U/L,24h生存组12例中有9例(75.0%),明显低于死亡组21例中有18例(85.7%)。且血清丙氨酸转氨酶活力与动脉二氧化碳分压(PCO2)呈显著正相关(r=0.56478,P<0.01),与氧分压PO2呈显著负相关(r=0.42548,P<0.05)。结论:心脏停搏患者自主循环恢复后的高丙氨酸转氨酶血症可能与肝脏缺血-再灌注损伤和原发疾病有关,并在估计患者预后方面有一定的意义。
Objective：To study the clinical significance of circulation in cardica arrest . Methods：Serum alanine aminotransferase were determined , and the changes in serum alanine aminotransferase activities were observed in 33 cases with cardiopulmonary resuscitation （CPR）. Results：Tbe incidenceog hyperalsnine-aminotransferesemia was81.8% （27 / 33）in CPR cases （40-249 U / L）. Only 9 outof 12 cases （75.0%）had serum alanine aminotransferase activity exceeding 40 U/L in the survived group within 24 hours, while 18 out of 21 cases in the fatal group （85.7%）. In addition, the levels of sermn alanine aminotrausferese positively correlated with PCO2 （r = 0.56478, P 〈0.0 l）and negatively correlated with PO2 （r = 0.42548,P〈0.05）. Conclusion：The hyperalsnine-aminotrausferasemia after recovery of spontancous c/rculation in cardica arrest might be related to liver ischemia-reperfusion injury and the primary disease .This can help us to estimate the prognosis of cardiac arrest.
出处
《实用中西医结合临床》
2006年第3期5-6,共2页
Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
关键词
心脏停搏
心肺复苏
丙氨酸特氨酶
血清
临床药理
Cardiac arrest
Cardiopulmonary resuscitation
Alanine aminotransferase
Blood serum
Cinical pharmacology
