摘要
目的探讨溃疡性结肠炎(UC)的临床特征及内镜表现。方法总结我院1984年10月至2004年12月经结肠镜检查及病理确诊的UC患者的相关资料,分析其内镜检查结果及临床特点。结果经结肠镜检查确诊的UC患者为802例,占同期结肠镜检查患者总数的4.7%;男女之比为1∶1.1;平均发病年龄为(39.3±13.0)岁,高峰年龄段为30～39岁。UC的发病率呈明显上升趋势。临床主要表现为黏液脓血便、腹泻和腹痛;5%的患者伴有肠外表现(关节炎、眼部疾病及皮疹等)。病变部位以直肠、乙状结肠多见(62%),病情以轻、中度为主(84%)。结肠镜诊断UC的准确率为95%。临床治疗以内科保守治疗为主,总有效率可达95%,药物主要有5!氨基水杨酸(5!ASA)、激素和抗生素等。结论UC的发病率呈明显上升趋势,病变以轻、中度为主,病变大部分局限在左半结肠。结肠镜对UC有较大的诊断价值。肠外表现及并发症较少见,5!ASA和激素治疗总体疗效好,手术率、死亡率和癌变率低。
Objective To analyze the clinical and endoscopic characteristics of the patients with ulcerative cohtis （UC）. Methods 802 UC patients diagnosed by china-Japan Friendship Hospital between 1984 and 2004 were studied. The data of clinical and endoscopy were collected and analyzed. Results 802 patients were diagnosed as UC, accounted for 4.7% of all patients who had endoscopy examination. The ratio of male to female was 1：1.1. The mean age at the onset was （39.3±13.0） years, and the peak age was between 30-40 years. The typical clinical manifestation of UC were bloody mucopurulent stool, diarrhea and abdominal pain. 5% of the UC patients had extra-intestinal manifestations. Among UC patients, 62% was proctitis or roctosigmoiditis. 84% of the UC patients met the criteria of mild or moderate grade. All these patients received the recommended treatment （including aminosalicylate, corticosteroid and antibiotics et al.）, and 95% patients responded well. Conclusions The incidence of UC has been markedly increased in recent years. The characteristics of UC are less severe and few extra-intestinal manifestations. The lesions of UC are commonly located in the left colon. Most patients responds well to the recommended treatment.
出处
《北京医学》
CAS
2006年第6期325-327,共3页
Beijing Medical Journal
关键词
溃疡性结肠炎
临床表现
结肠镜
病理
Ulcerative colitis Clinical manifestation Colonoscope Pathology
