摘要
为探讨雌激素对NK细胞的作用,在不同时间把不同剂量的雌激素加入培养体系中,分析雌激素对无和有外来刺激原刺激NK细胞的影响。结果显示培养开始加入生理剂量、低于生理剂量和超生理剂量的雌激素均可明显抑制NK细胞的增殖;培养48 h后加入相同剂量的雌激素,生理剂量和低于生理剂量雌激素仍可明显抑制NK细胞的增殖,超生理剂量雌激素非但不能抑制反而使NK细胞的数量增加。
To ohserve the effects of estradiol on natural killer （NK） cells, different doses of estradiol were added to the cuhur al systerm at different time and the effects of estradiol on the unactivated and activated NK cells were studied in the present study. The experimental results showed that the normal, lower and higher levels of estradiol all could suppress the growth of NK cells, if they were added into cell culture plates at the beginning of cell culture. But their growth did not suppress but increased, when the higher dose of estradiol was put into cell culture plates after 48 hours of cultivation.
出处
《现代免疫学》
CAS
CSCD
北大核心
2006年第3期247-250,共4页
Current Immunology
