摘要
目的研究佝偻病与影响小儿生长发育诸因素之间的关系,进一步探讨本病的发病机制,为临床提供相应的治疗对策。方法本研究将184例门诊佝偻病患儿按有无佝偻病症状分为两组,同时实施了末梢血系列、骨源性碱性磷酸酶(BALP)的实验室检查,以及一般情况调查问卷,资料应用SPSS 10.0软件进行t检验,Spearm an等级相关分析。结果有症状组患儿较无症状组患儿MCV、MCHC、RDW明显升高(P<0.05),而有症状组患儿的RBC记数与无症状组患儿比较有所下降(P<0.05);对患儿性别、出生体重、母亲分娩情况、母亲孕期腿痉挛、喂养史及患儿佝偻病体征(肋缘外翻、方颅、鸡胸)做Spearm an等级相关分析,母亲孕期腿痉挛分别与方颅、鸡胸、肋缘外翻等佝偻病体征呈显著正相关(r=0.480、r=0.563、r=0.633,P<0.01),佝偻病体征如方颅、鸡胸、肋缘外翻之间也有正相关性(P<0.05)。结论1、有症状的佝偻病患儿贫血更严重,2、母亲孕期钙营养不足。
Objective ： To investigate the association between the rickets and a series of factors which affect the growth of children, exploring the mechanism about rickets in order to provide the method to cure the rickets. Method： 184 rickety infants and children were devidod into two groups as rickety symptom, Then they were implemented blood series , blood BALP and general situation questionnaires, The data were analysed by SPSS 10, 0 software. Results： The levels of blood MCV, MCHC, RDW in the symptom group were significantly higher than those in the no symptom group （ P 〈 0.05）, the level of RBC in the symptom group was lower than that in the no symptom group （ P 〈 0.05）. Spearman correlation analysis indicated there were significant passive correlation between the calcium deficiency in pregnant women and rickets （ P 〈0. 05） such as chicken breast, caput quadrature, rib convex. Conclusion： The rickety infants and children who have more significant anaemia symptom than those who have no rickety symptom. The calcium deficiency in pregnant women is more likely to lead to the rickets in infants and children.
出处
《中国优生与遗传杂志》
2006年第6期117-118,共2页
Chinese Journal of Birth Health & Heredity
关键词
佝偻病
贫血
钙营养
婴幼儿
孕期
Rickets
Anaemia
Calcium nutrition
Infants and children
Pregnancy
