恩丹西酮复合曲马多用于腰硬联合麻醉后寒颤观察被引量：11

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摘要目的:探讨腰硬联合麻醉后寒颤的最佳药物治疗方案。方法:选择120例ASAⅠ～Ⅱ级,腰硬联合麻醉下行下腹部下肢手术患者,随机分为4组,生理盐水组(N组)、恩丹西酮组(E组)、曲马多组(T组)、恩丹西酮复合曲马多组[(E+T)组]。患者入室开放静脉通路后,N组给予生理盐水10mL,E组给予恩丹西酮8mg1min内静脉注射(用生理盐水稀释到10mL),T组给予曲马多100mg1min内静脉注射(用生理盐水稀释到10mL),(E+T)组是在E组的基础上,患者行麻醉穿刺后,消毒皮肤前静脉缓慢注射50mg曲马多(用生理盐水稀释到5mL),观察记录术中寒颤及恶心呕吐等发生的情况,并持续监测呼吸循环的变化,测定麻醉阻滞平面。结果:寒颤发生率N组为50.0%,E组为13.5%,T组为6.7%,(E+T)组为3.3%。N组与E、T、(E+T)组比较差异有显著性(P<0.01),(E+T)组与E、T组比较差异无显著性(P>0.05),4组围术期呼吸循坏变化差异无显著性(P>0.05);恶心呕吐发生率N组为20.0%、E组为6.6%、T组为26.5%、(E+T)组为0,4组进行比较,E、(E+T)组与N、T组比较差异有显著性(P<0.05),而E组与(E+T)组比较,N组与T组比较差异无显著性(P>0.05)。结论:麻醉前静脉注射恩丹西酮8mg复合皮肤消毒前静脉注射曲马多50mg对麻醉后寒颤起到很好的预防和治疗作用,并大大降低了恶心呕吐发生率。

作者王晓燕

机构地区浙江省乐清市人民医院麻醉科

出处《实用医学杂志》 CAS 2006年第11期1306-1307,共2页 The Journal of Practical Medicine

关键词寒战腰硬联合麻醉恩丹西酮曲马多

分类号 R614 [医药卫生—麻醉学]

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