摘要
目的探讨舒利迭（吸入型肾上腺皮质激素与长效β2-受体激动剂的预混制剂）联合双水平气道正压通气（BiPAP）对稳定期慢性阻塞性肺疾病（COPD）的治疗作用.方法稳定期COPD病人52例,舒利迭TM50/250,1吸/次,2次/d;BiPAP,吸气压力（IPAP）10～20cmH2O,呼气压力（EPAP,也称PEEP）3～6cmH2O,吸氧浓度（FiO2）3L/min,每天夜间通气6～8h.观察治疗前、治疗后12周病人临床症状、生活质量、健康状态和肺功能.结果治疗前、治疗后12周病人的临床症状、急性加重次数及严重程度、健康状态和生活质量、肺功能等指标比较差异有统计学意义（P＜0.05）.结论舒利迭联合BiPAP治疗稳定期COPD病人能够明显改善其症状,提高生活质量,有一定的临床应用价值,对减缓COPD病人肺功能下降有积极意义.
Objective To investigate the treatment effect of seretide accuhaler （ mixture preparation of long. acting 62 adrenergic receptor atagonist and inhaled corticosteroid ） combined with BiPAP on COPD patients at stable stage. Methods Fifty - two COPD patients at stable stage were treated with seretide aeeuhaler TM 50/250 by accuhaler/diskus, 2 times per day, and BiPAP （IPAP 10 -20cm H2O,EPAP 3 -6era H2O, FiO2 3L/min）6 -8h every night. After 12 weeks, clinical symptoms, quality of life and lung functions were evaluated respectively before and after treatment. Results After treatment, the observed indexes were significant improved （ P 〈 0.05 ）. Conclusion Treatment with seretide accuhaler combined with BiPAP in COPD can improve clinical symptoms and quality of life. It has certain value of clinical application, and it can step down the decrease of lung function in COPD patients.
出处
《中原医刊》
2006年第11期7-8,共2页
Central Plains Medical Journal
关键词
慢性阻塞性肺疾病
稳定期
舒利迭
无创正压通气
Chronic obstructive pulmonary disease
Stable stage
Seretide accuhaler
Noninvasive positive ventilation
