摘要
应用1D NMR、2D NMR(COSY、HMQC、HMBC、NOESY)及脉冲梯度场2D NMR技术[gHSQC(1H-15N)、gHMBC(1H-15N)]深入研究了第四代新型超广谱头孢菌素类抗生素硫酸头孢匹罗的结构,并首次对其1H NMR、13C NMR谱和15N NMR谱的信号进行了全归属,通过NOESY实验对其立体结构提供有力依据.
The structure of cefpirome sulfate, a new compound belonging to the fourth generation super broad-spectrum cephalosporins antibiotics, was studied using 1D and 2D NMR techniques. Complete assignments of the ^1H, ^13C and ^15N NMR chemical shifts were obtained. The structural parameters obtained from the NOESY experiment were found to be useful for determining its stereo-structure.
出处
《波谱学杂志》
CAS
CSCD
北大核心
2006年第2期253-259,共7页
Chinese Journal of Magnetic Resonance
