Iodine-catalyzed Synthesis of α-Amino Phosphonates
Iodine-catalyzed Synthesis of α-Amino Phosphonates
摘要
Iodine was found to be an efficient catalyst for the one pot synthesis of α-amino phosphonate from aldehydes, anilines and diethyl phosphite. The influences of the iodine loading, reaction solvent, the structure of aldehyde and aniline on the reaction were studied.
基金
Financial support for this research was provided by the National Natural Science Foundation of China （No.20472061） and Sun Yat-sen University.
参考文献11
-
1[1]a) Fields,S.C.,Tetrahedron,1999,55,12237.b) M.C.Allen,W.Fuhrer,B.Tuck,et al.,J.Med.Chem.,1989,32,1652.c) P.P.Giannousis,P.A.Bartlett,J.Med.Chem.,1987,30,1603.d) P.Kafarski,B.Lejczak,Phosphorus,Sulfur,Silicon Relat.Elem.,1991,63,1993.e) F.R.Atherton,C.H.Hassall,R.W.Lambert,J.Med.Chem.,1986,29,29.
-
2[2]a) S.Laschat,H.Kunz,Synthesis 1992,90.b) J.S.Yadav,B.V.S.Reddy,K.S.Raj,et al.,Synthesis,2001,2277.c) B.C.Tanu,A.Hajra,U.Jana,Org.Lett.,1999,1,1141.
-
3[3]a) H.Firouzabadi,N.Iranpoor,S.Sobhani,Synthesis,2004,2692.b) R.Ghosh,S.Maiti,A.Chakraborty,et al.,J.Mol.Catal.A:Chem.,2004,210,53.c) C.T.Qian,T.S.Huang,J.Org.Chem.,1998,63,4125.
-
4[4]F.Xu,Y.Q.Lou,M.Y.Deng,et al.,Eur.J.Org.Chem.,2003,4728.
-
5[5]S.Chandrasekhar,S.J.Prakash,V.Jagadeswar,et al.,Tetrahedron Lett.,2001,42,5561.
-
6[6]J.S.Yadav,B.V.S.Reddy,C.Madan,Synlett,2001,1131.
-
7[7]S.Iimura,D.Nobutou,K.Manabe,et al.,Chem.Commun.,2003,1644.
-
8[8]K.Ramalinga,P.Vijayalakshmi,T.N.B.Kaimai,Tetrahedron Lett.,2002,43,879.
-
9[9]P.Phukan,J.Org.Chem.,2004,69,4005.
-
10[10]J.W.Sun,Y.M.Dong,L.Y.Cao,et al.,J.Org.Chem.,2004,69,8932.
