摘要
作者报告用佳代胞（济南假单胞菌注射液，ＰＶＩ）治疗４６例癌性胸腔积液的结果，以治疗顺序分组为ＰＶＩ加化疗组和单用ＰＶＩ组。按Ｍｉｌｌａｒ制定的标准评定疗效。总有效率（ＣＲ＋ＰＲ）９１．３％，两组间疗效无统计学差别。既往局部用药与既往未治者的疗效亦无统计学差异。ＰＶＩ的副作用主要是发热（６７．４％），术前给予吲哚美辛和地塞米松对疗效无不良影响，并可减少发热的出现率（Ｐ＜０．０５）。
The results of 46 cases with malignant pleural effusion treated with PVI (Pseudomonas Vaccine Injection) are reported. All these cases were classified according to the order of treatment into two groups:the group of PVI plus chemotherapy (group A) and PVI alone (group B). The standard of Millar's was used to evaluate the curative effect. The total response rate (CR + PR ) was 91. 3%. We found that there was no statistical difference between groups A and B,nor between those patients treated and never treated before. The main side effect of PVI was fever (67.4%). Using indomethacin and /or dexamethasone before intrapleural PVI can decrease the incidence of fever (P<0.05), and no adverse effects were found.
出处
《河南肿瘤学杂志》
1996年第1期53-54,共2页
Henan Journal of Oncology
