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两性霉素B脂质体治疗白血病合并霉菌性肺炎6例 被引量:3

Liposomal amphotericin B for the treatment of 6 fungal pneumonia children with leukemia
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摘要 目的:探讨白血病患儿霉菌性肺炎的临床特征及两性霉素B脂质体的临床疗效和不良反应。方法:回顾性分析我院2004~2006年确诊为白血病合并霉菌性肺炎6例的临床表现和诊疗过程。结果:6例白血病患儿病原菌培养均为霉菌,两性霉素B脂质体治疗真菌感染疗效满意,主要不良反应是低钾血症。结论:霉菌是引起白血病患儿化疗后院内感染重要病原菌之一,肺炎常规治疗临床改善不明显时,要重视霉菌检查并及时改用两性霉素B治疗。 Objective:To investigate the clinical feathers of leukemia children with fungal pneumonia, assess the curative effects and adverse reaction of liposomal amphotericin B. Methods: To retrospective review the clinical feathers and antl-fungi therapy of 6 leukemia children with fungal pneumonia between 2004 and 2006. Results: Pathogen of infection was fungi, liposomal amphotericin B was curative and the main adverse reaction was hypokaliemia. Conclusions: Fungi was one of the important pathogens of infection in hospital with leukemia children received chemical therapy, exam of fungi and chemical therapy of amphotericin B are important ff routine therapy has no effect.
出处 《儿科药学杂志》 CAS 2006年第3期51-52,共2页 Journal of Pediatric Pharmacy
关键词 两性霉素B脂质体 霉菌感染 白血病 Liposomal amphotericin B Fungal infection Leukemia
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