摘要
目的研究心功能正常的非永久性心房颤动患者转为窦性心律前后血浆脑钠肽(BNP)水平的变化,探讨血浆BNP水平在预测房颤发生和预后中的作用。方法测定128例心功能正常的非永久性房颤患者电复律前后血浆BNP变化,并与67名正常窦性心律、心功能正常者作比较。结果房颤患者在电复律成功后2h内,血浆BNP水平明显降低。54名阵发性房颤患者全部转为窦性心律,血浆BNP水平由复律前的68.4±18.7ng/L降至28.1±14.9ng/L;74例持续性房颤患者全部转为窦律,血浆BNP水平由复律前的75.8±20.9ng/L降至29.1±18.1ng/L。结论血浆BNP低水平增高可能预示无症状心脏病患者房颤的发生,房颤患者BNP水平在正常范围内的下降可能预示房颤的终止。
Objective To study the changes of plasma brain natriuretic peptide （BNP） levels before and after cardioversion in non-permanent atrial fibrillation （AF） patients with normal left ventricle function, and to explore the role of BNP in AF. Methods Plasma BNP levels were measured in 128 non-permanent atrial fibrillation patients and 67 health persons with sinus rhythm. Results Two hours after successful cardioversion, plasma BNP levels were decreased significantly in an tbe patients. Fifty four patients with paroxysmal atrial fibrillation were all restored to sinus rhythm ,and the average level of plasma BNP was dropped from 68.4 ± 18.7 ng/L to 28.1 ±14.9ng/L. Seventy four patients with persistent atrial fibrillation were restored to sinus rhythm, and the average level of plasma BNP was dropped from 75.8 ±20.9ng/L to 29.1±18. lng/L. Conclusion Increasing of plasma BNP in normal low level maybe predict AF occurrence in asymptomatic patients with heart disease, and the decreasing within the normal range in AF patients maybe predict AF termination.
出处
《现代实用医学》
2006年第4期221-222,225,共3页
Modern Practical Medicine
关键词
心房颤动
利钠肽
脑
电抗休克
Atrial fibrillation
Natriuretic peptide,brain
Electric eountershock
