摘要
目的研究重组白细胞介素11(rhIL-11)对成人初治的急性白血病化疗后血小板明显减少的疗效。方法初治的急性白血病化疗后首次血小板计数<20×109/L作为研究对象,分治疗组和对照组,治疗组用rhIL-11治疗,分别统计两组每个患者首次血小板计数<20×109/L恢复至20×109/L、50×109/L及100×109/L以上的时间。结果两组两两比较治疗组血小板计数恢复时间均明显缩短(所有P=0.00)。结论rhIL-11可明显加速初治急性白血病化疗后血小板的恢复,使用较安全。
Objective To study the efficacy of recombinant human interleuldn- 11 （ rhIL- 11 ） in the treatment of initial chemotherapy-induced thrombocytopenia in adult acute leukemia. Methods Patients with acute leukemia were enrolled when platelet count dropped below patient after chemotherapy. Then they were divided into treated group and control group, rhIL-11 was used in treated group. The time each patient needed for his/her thrombocyte reaching 20 × 10^9/L,50 × 10^9/L and 100 × 10^9/L was recorded respectively. Results The thromhocyte recovery time in the treated group was obviously shortened compared with the control group（ P = 0.00 ）. Conclusion rhIL- 11 can reduce thromhocytopenia induced by initial chemotherapy in adult acute leukemia and is a safe drug ：[or treatment.
出处
《中国基层医药》
CAS
2006年第4期607-608,共2页
Chinese Journal of Primary Medicine and Pharmacy
基金
浙江省温州市科技发展计划资助项目(Y2003A111)
