摘要
目的探讨冠心病介入治疗的效果及对血管内皮生长因子(VEGF)和C-反应蛋白(CRP)水平的影响。方法127例心绞痛和心肌梗死患者,行PCI(PTCA/PTCA+支架术),观察疗效,测定CRP和VEGF在手术前后的变化。结果127例患者共安置支架146枚,支架全部成功地置入靶血管病变部位;有2例双支病变患者因导丝不能通过前降支狭窄部位放弃,4例患者发生无再流现象,手术成功率为95.3%。CRP的水平术后增加142.9%,而VEGF术后减少31.9%。结论PCI对冠心病的治疗效果是满意的,监测血清中CRP和VEGF可了解治疗效果和炎症程度。
Objective To investigate the therapeutic efficacy of coronary heart disease intervention and effect on vascular endothelial growth factor（VEGF） and C-reactive protein（CRP） levels. Methods 127 cases with angina and myocardial infarct were done PCI（PTCA/PTCA percutaneous transcoronary angioplasty ＋ stenting）, the therapeutic efficacy was observed,and perioperative VEGF and CRP levels were determined. Results 146 brackets cases were placed in 127 cases, all brackets were successfully inserted into target vascular lesion sites;2 cases with two rami pathological changes given up PTCA because guide wire couldn＇t pass anterior descending branch narrow part ;4 cases took place no re-flow phenomenon,operation achievement ratio was 95.3 %, The levels of post-operative CRP increased 142.9% , but the levels of post-operative VEGF decreased 31.9 %. Conclusion The therapeutic efficacy PCI on coronary heart disease is satisfactory monitoring CRP and VEGF in blood serum could be helpful to understand the therapeutic efficacy and inflammation degree.
出处
《中国基层医药》
CAS
2006年第4期575-576,共2页
Chinese Journal of Primary Medicine and Pharmacy
