摘要
恶性肿瘤的治疗以多学科、多手段的综合治疗为原则。虽然在临床应用时需考虑多种因素,但半个多世纪以来,绝大多数肿瘤医师已肯定这一原则。对头颈部肿瘤(主要为鳞状细胞癌)的中晚期(III及IⅣ期)病变,联合应用放射及手术(术前或术后放疗)治疗,其效果(以5年生存率为统计要求)优于单一治疗手段已经被临床实证充分肯定。但化疗的应用是否能够提高头颈部实体瘤如鳞癌的疗效,仍然存在争议。
It has been expected that chemotherapy,as one of the major modalities in the management of cancer,would exert some beneficial effects on head and neck tumors.However,most of the pathologic types of head and neck solid carcinoma are of squamous cell variety,which seems no long-term radical response to any regimens of chemotherapy so far,according to the literature reports since the advent of chemotherapy.It is suggested at present no chemotherapy be applied to head and neck cancer patients for the purpose of a radical cure,which could be brought about by surgery or radiotherapy.Some of the literature that advocated chemotherapy on head and neck cancer is unjustifiable,not without personal bias.Clinical investigation should be further conducted on a small scale and in a rigorous way at research units in order to find a curative and treatment advice for head and neck oncologists in future.
出处
《中国口腔颌面外科杂志》
CAS
2006年第3期162-165,共4页
China Journal of Oral and Maxillofacial Surgery
