摘要
目的观察舒血宁注射液联合低分子肝素治疗不稳定型心绞痛(UAP)的临床疗效。方法79例UAP患者,分为两组,治疗组40例,对照组39例。治疗组在常规治疗的基础上采用舒血宁注射液静滴联合皮下注射低分子肝素。对照组仅行常规治疗。两组疗程均为7 d。治疗前后观察心绞痛发作次数、心电图ST段变化,监测血小板、凝血酶原时间(PT),激活部分凝血活酶时间(APTT)。结果两组均能明显控制心绞痛的发作次数(P<0.05),但治疗组更能显著降低心绞痛的发作(与对照组比较,P<0.05)。治疗前后治疗组血小板、PT、APTT无显著变化。结论舒血宁注射液联合低分子肝素是治疗UAP的一种安全、有效的方法。
Objective To investigate the therapeutic effect of Shuxuening injection combined with low molecular heparin in treating of unstable angina pectoris（UAP）. Methods 79 patients with UAP were divided into two groups randomly, 40 for treatment group, 39 for control group. The control group was treated with conventional therapy, the treatment group was treated with conventlonal therapy combined with intravenous drip Shuxuening injection and low molecular heparin 0.4ml, twice daily subcutaneously for 7 days. The frequency of angina pectoris attacks, ST-T changes on the ECG,PLT,PT, APTT were observed. Results The frequency of angina pectoris attacks were decreased in two groups （ P 〈 0.05 ）, were significant decreased in treatment group （compared with control group, P 〈 0.05 ）. There were no significant differences in blood platelet, PT, APTT after treatment in treatment group（ P 〉 0.05 ）. Conclusion Shuxuening injection combined with Low molecular heparin are effective and safety in the treatment of UAP.
出处
《临床和实验医学杂志》
2006年第3期203-204,共2页
Journal of Clinical and Experimental Medicine
关键词
舒血宁注射液
低分子肝素
不稳定型心绞痛
Shuxuening injection
Lowmolecular heparin
Unstable angina pectoris
