摘要
目的:总结强直性脊柱炎(AS)的临床特点,提高诊治水平。方法:回顾性分析56例强直性脊柱炎患者的临床资料。结果:56例强直性脊柱炎中,男50例,女6例,平均发病年龄28岁;首发症状为慢性腰痛者43例占76.78%;关节外表现仅见虹膜炎10例占17.85%;骨盆正位片全部有骶髂关节炎占100%;HLA-B27阳性52例占92.85%;25例误诊占44.64%;治疗药物主要有非甾体类抗炎药(NSAID s)、柳氮磺胺吡呤(SSZ)、甲氨蝶呤(MTX)、糖皮质激素等。结论:强直性脊柱炎多见于青年男性,其首发症状多为慢性腰痛,临床易误诊,骨盆正位片、骶髂关节炎及HLA-B27阳性有助于早期诊断和治疗。
Objective： To analyze the clinical characters of ankylosing （AS） and improve the effect of diagnosis and treatment of AS. Methods： The clinical of 56 patients, with AS diagnosed and treated from 1992 to 2004were analyzed retrospectively. Results： of the 56 patients, 50 were male and 6 female, the average age at onset of disease was 28 years old. Chronic back pain, as the initial symptom at onset was observed in 43（76.78） ; iritis, the only clinical feature other than signs of the joints, was observed in 10（ 17. 85% ） ; pelycographic sacroiliitis, were shown in all 56（ 100% ） patients and HLA - B27 was present in 52（92% ）. Misdiagnosis was made in 25 （44.64%）. The major drugs used for AS were NSAIDs SSZ, MTX, glucocorticoid etc. Conclusion ： AS occurs more frequently in young men. In most patients with AS the initial symptom is chronic back pain and may be easily misdiagnosed. Sacroiliitis on pelycogram and positive HLA - B27 test are helpful to early diagnosis and treatment of AS.
出处
《赣南医学院学报》
2006年第2期205-206,共2页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
