摘要
[目的]了解豫东南某县农村艾滋病病毒(HIV)感染者CD4、CD8 T淋巴细胞水平,以便选择治疗方案,及时进行治疗。[方法]2005年4月,采用流式细胞仪(FCS)对豫东南某县农村658名HIV感染者进行CD4、CD8 T淋巴细胞计数和CD4/CD8比值检测。[结果]HIV感染者的CD4 T淋巴细胞计数为(318.03±196.39)个/μl,<500个/μl的占83.59%,<200个/μl的占29.94%;CD8T淋巴细胞计数为(966.51±437.50)个/μl;CD4/CD8比值为(0.38±0.28);不同性别、不同年龄HIV感染者的CD4、CD8和CD4/CD8的差异均无统计学意义(P>0.05)。[结论]农村HIV感染者存在不同程度的免疫功能损害,大部分人已进入艾滋病的中、晚期。
[Objective]To analyze the situation of the T lymphocyte subsets among HIV infectors in order to select treatment scheme and the patients were treated promptly. [Methods]The cell counts of CD4.CD8 and CD4/CD8 ratio from 658 blood speciments of HIV infectors were detected by FCS respectively during April 2005. [Results]The mean vale of CD4 ,CD8 and CD4/CD8 ratio were （3.18. 03 ± 196.39 ） cells/μl, （966.51 ± 437.50） cells/μl, （0.38 ± 0.28）83.59% of them had CD4T cell counts lower than 500 cells/μl , and 29.94% had a figure lower than 200 cells/μl. There were no statistical differences in CD4,CD8 vale and CD4/CD8 ratio on persons with HIV infection between different gender and age groups. [Conclusion]The cell immune function of HIV infectors were impaired at different extent in the rural area . Most of them had been seen in a metaphase or later stage of AIDS.
出处
《预防医学论坛》
2006年第3期296-297,共2页
Preventive Medicine Tribune
