摘要
[目的]了解德州市健康人群A群与C群流行性脑脊髓膜炎(下称流脑)抗体水平,为预防流脑提供科学依据。[方法]2003年12月对德州市386名健康人血清采用酶联免疫吸附试验检测流脑A群、C群IgG抗体。[结果]检测血清386份,A群抗体阳性率96.11%,GMT 1∶20.59,不同地区、不同年龄组抗体阳性率差异无统计学意义(P>0.05);C群抗体阳性率19.95%,GMT 1∶4.50,不同地区、不同年龄组抗体阳性率差异有统计学意义(P<0.01、0.05)。A、C群性别之间抗体阳性率差异均无统计学意义(P>0.05)。[结论]德州市部分健康人群对A群脑膜炎双球菌有较高的免疫力,在加强A群流脑预防监测的同时,亦应强化C群流脑的预防监测。
[Objective] To understand antibody level of group A and group C epidemic cerebrospinal meningitis in healthy population in Dezhou. [Methods]To test IgG antibody of group A and group C epidemic cerebrospinal meningitis by ELISA for 386 persons. [Results]The antibody's positive rate of group A was 96.11%, those of different areas and different ages had no obvious differences (P 〉0. 05), GMTI was 20. 59. The antibody's positive rate of group C was 19.95% ,those of different areas and different ages had statistic significance ( P〈0. 01,0. 05),GMT1 was 4.50. Both two groups had no statistic significance between men and women ( P 〉0. 05). [Conclusion]Some healthy people in Dezhou had obvious immunity for group A epidemic cerebrospinal meningitis,Surveillance and prevention on group C epidemic cerebrospinal meningitis should be strengthened.
出处
《预防医学论坛》
2006年第3期290-291,共2页
Preventive Medicine Tribune
关键词
流行性脑脊髓膜炎
抗体
A群
C群
Epidemic cerebrospinal meningitis
Antibody
Group A
Group C