摘要
目的:探讨年轻妇女子宫内膜癌的临床和病理特点。方法:对16例45岁以下子宫内膜癌患者的临床病理资料进行回顾性分析。结果:年轻妇女子宫内膜癌占内膜癌总数的12.3%,随年龄的增加发病人数有增加的趋势。临床主要表现为月经失调(56.25%),阴道不规则出血(43.75%),不孕(50%)。病理检查子宫内膜样腺癌13例,腺鳞癌2例,浆液性乳头状腺癌1例。子宫内膜样腺癌组织学特点是腺体不规则,融合,乳头状结构,极性消失,腺上皮核大变圆,空泡状,核仁清楚。子宫内膜间质消失代之以肉芽组织或促纤维形成的间质反应。多数仅累及浅肌层。皆无转移。术前分段诊断性刮宫准确率较高。结论:45岁以下妇女的子宫内膜癌多数为高分化子宫内膜样腺癌,对月经不调或不孕合并子宫增大的肥胖妇女采用分段诊刮活检,有助于早期诊断。
Objective：To study the clinicopathologica ods：The retrospective analysis was performed to 16 cases features of endometrial carcinoma in younger women. Methunder 45 years old of endometrial cancers. Results：Young women＇s cases accounted for 12.3 G of endometrial cancers, and there was incremental tendency of incidence accompany with increasing of age. The major clinical manifestations were menstrual disorder （56.25%）,vaginal irregular hleeding （ 43. 75% ）, and infertility （50%）. There were 13 endometrioid adenocarcinomas, 2 adenosquamous carcinomas, and 1 serous papillary adenocarcinoma. The histological features of endometriold adenocarcinomas were irregular confluence, and papillar glandular patterns ;enlarged,round and vacuolus nuclei,prominent nucleoli;disappearance of stroma,and replaced with granulation tissue or desmoplastic response of stroma. The major just involved superficial muscular layer and no metastasis, Preoperative segmenting diagnostic curettage had a high accuracy. Conclusions：The major of endometrial cancers of women under 45 years old are high grade endometrioid adenocarcinomas. It is helpful for early diagnosis to apply segmenting diagnostic curettage for obese women of menoxenia or infertility complicating hysterauxesls.
出处
《中国误诊学杂志》
CAS
2006年第10期1849-1851,共3页
Chinese Journal of Misdiagnostics
