摘要
测定３５例青紫型先天性心脏病患儿红细胞、血浆丙二醛（ＭＤＡ）含量、红细胞膜微粘度及血液流变学指标。结果患儿红细胞、血浆ＭＤＡ、膜微粘度、全血粘度、红细胞比积、红细胞聚集指数、刚性指数均显著高于正常组；ＭＤＡ含量，膜微粘度、红细胞刚性指数、聚集指数及全血粘度之间均存在正相关关系。提示患儿红细胞脂质过氧化反应增强，导致膜流动性降低、红细胞变形性差，聚集性增加，可能是血液粘度增加较为主要的原因。
alondiadehyde(MDA) of erythrocyte and plasma ,erythrocytic membrane microviscosity,and parameters of hemorrheology were determined in 35 children with Cyanotic Congenital Heart Disease(CCHD) and compared with 3 6 normal children.The results showed that the MDA lev-els,microviscosity,whole blood viscosity,erythrocytic rigidity and aggregation were significantly increased in the patients than those in the normal children.There were positive correlations be-tween these parameters above in the patients.The findings indicate that the injury from lipid per-oxidation on erythrocyte membrane , which causes lower ervthrocvtic membrane fluidity and de-formability. may be one of main causes inducing higher blood viscosity in CCHD.
出处
《基础医学与临床》
CSCD
1996年第3期211-214,共4页
Basic and Clinical Medicine
基金
广西卫生厅青年科学基金
关键词
心脏缺损
先天性
过氧化脂质
紫绀型
儿童
Heart defects congenital Lpid Peroroxide Membrane fluidiy Blood viscosity
