摘要
目的探讨哮喘完全控制时气道炎症状态。方法哮喘患者36例,均按获得最佳哮喘控制研究的方法进行治疗,并测定肺功能和诱导痰细胞学分类。结果治疗后完全控制组肺功能改善更加明显,与非完全控制组的差异具有显著性(P<0.05);诱导痰嗜酸性粒细胞明显下降,与治疗前的差异具有显著性(P<0.05),但2组间差异无显著性。结论哮喘达到完全控制时,肺功能改善明显,但气道炎症并没有得到完全控制,与非完全控制者类似,仍然需要继续治疗。
Objective To explore the state of airway inflammation under the complete control of asthma. Methods There were 36 cases of asthma that were treated by the method of the best control of asthma. Induced sputum and pulmonary function were detected. Results After treatment, the pulmonary function was more obviously improved in complete control group than in non-complete control group （ P 〈 0.05 ）, and induced sputum eosinophils count was obviously decreased, with significant difference compared with that before treatment （ P 〈 0.05 ）, but there was no significant difference between the two groups. Conclusion The pulmonary function is improved apparently when asthma has been completely controlled, but the airway inflammation has not been totally Controlled, which is the same as non-complete control group, so it needs further treatment.
出处
《中国综合临床》
北大核心
2006年第6期511-513,共3页
Clinical Medicine of China
基金
广东省医学科研基金(A2005351)
2004年度暨南大学临床学院科研培育基金(200415)
关键词
哮喘
诱导痰
气道炎症
Asthma
Induced sputum
Airway inflammation
