摘要
在兽药的免疫化学残留分析中,能否合成稳定的具有良好免疫原性的人工抗原是制备抗体和建立免疫分析方法的最关键步骤。综述了国内外兽药人工抗原合成过程中载体的选择、半抗原的设计(强调偶联部位和间隔臂的引入)、半抗原与载体的偶联方法、人工抗原的纯化与鉴定等方面的研究进展。
The key to using immunoassay method in veterinary drug residue analysis is drug artificial antigen. The progress of carrier selection, design of hapten (emphasizing the synthesis of veterinary hapten-carrier coupling position, attachment of connecting arm), methods for the synthesis of hapten-protein conjugation, purification and identification of artificial antigens were introduced in this paper.
出处
《中国兽药杂志》
2006年第5期44-47,共4页
Chinese Journal of Veterinary Drug
关键词
兽药
半抗原
人工抗原
合成
进展
veterinary drug
hapten
artificial antigens
synthesis
progress