摘要
目的:研究呼吸机相关性肺炎(VAP)的发病率、病死率、危险因素及病原菌分布,探讨预防措施。方法:对65例机械通气患者的临床资料进行回顾性分析。结果:本组VAP的发生率为43.08%,病死率为46.43%。VAP的发生与年龄、机械通气时间、鼻饲、抑酸剂及抗生素的应用有关。共检出病原菌54株,其中革兰阴性菌45株,占83.33%,前三位致病菌依次为铜绿假单胞菌、嗜麦芽窄食单胞菌和木糖氧化产碱杆菌;革兰阳性菌4株,占7.41%;真菌5株,占9.26%。结论:危险因素的存在与VAP的发生密切相关。主要致病菌为铜绿假单胞菌和嗜麦芽窄食单胞菌。
Objective： To study the morbility, mortality, risk factors and pathogen of ventilator-associated pneumonia （VAP） for the decision of the prevention strategies. Methods： The clinical data of 65 patients received mechanical ventilation were retrospectively analyzed. Results： The morbidity and mortality of VAP were 43.08% and 46.43%. Age, period of mechanical ventilator, nasogastric feeding, use of antiacid and antibiotics were related to the development with VAP. Fifty- four strains of pathogens were isolated from 28 cases with VAP, the percentages of Gram-negative bacilli, Gram-positive cocci and fungi were 83.33%, 7.41% and 9. 26% respectively. Pseudomonas aeruginosa, Stenotrophornonas rnaltophilia and Achrornobacter xylosoxidans were the most common pathogens. Conclusion： The presence of risk factors is correlated with VAP. The main pathogens are Pseudornonas aeruginosa and X. Maltophilia.
出处
《武汉大学学报（医学版）》
CAS
2006年第3期412-414,共3页
Medical Journal of Wuhan University
