摘要
目的:研究脂肪肝及脂肪性肝炎的流行现状与危险因素。方法:随机抽取湖北省武汉市水果湖地区体检人员3 649人,测定体重指数(BMI),检测空腹血糖(FBS)、谷丙转氨酶(ALT)、胆固醇(TC)、甘油三脂(TG)等生化指标及肝脏B超。结果:共检出脂肪肝913人,患病率为25.01%,其中男722例(79.1%),女191例(20.9%)。脂肪肝发生随年龄上升而上升,男性50-60岁患病率最高,女性60-70岁最高。脂肪肝随BMI上升而上升,体重、身高资料齐全者880人,超重者及肥胖者808例(91.8%),其中肥胖者占68.1%。脂肪肝伴发高血压病者214例(23.4%),空腹血糖大于6.1 mmd/L者258例(28.3%),高血脂症者604例(66.2%)。脂肪性肝炎发病率6.4%。结论:随着生活水平的提高,城市脂肪肝发病率直追发达国家,男性明显大于女性,60岁以后女性发病率大于男性。男性、高脂血症、肥胖、高血压、糖代谢紊乱为脂肪肝危险因素。
Objective： To investigate the prevalence rate and risk factors of fatty liver in Wuhan city, China. Methods： The study involves 3 649 persons in Wuhan Shuiguohu area of Hubei province and their height, weight, limosis blood suger, alanine aminotrans ferase（ALT）, total cholesterin （TC）, total glycerin （TG）and ultrasonographic results were recorded and analyzed. Results： There have 913 cases of fatty liver in our study,with 722（79. 1%） males and 191（20.9%） females. The total incidence of fatty liver was 25.0%. The fatty liver incidence increased with age. The highest incidence of male fatty liver was in 50-60 years group, and that of the female was in 60-70 years group. The fatty liver increased with BMI. In our study, 808 cases（91.8%） had overweight and adiposity, and 599 cases（68. 1%） had adiposity. The incidence of steatohepatitis was 6.4%. Conclusion： With the improving of living condition, city incidence of fatty liver is increasing to the level of developed countries. The male incidence is higher than female except for the population of 60 years old or older. Male, dyslipid, obesity, hypertension and fasting hyperglycemia are risk factors of fatty liver.
出处
《武汉大学学报（医学版）》
CAS
2006年第3期319-322,共4页
Medical Journal of Wuhan University
