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瑞芬太尼与呼吸抑制 被引量:2

Remifentanil and Kespiratory Depiession
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摘要 新型阿片类药瑞芬太尼因化学结构独特而具有起效快,清除快等特点,已广泛应用于临床麻醉与镇痛,然而其呼吸抑制的不良反应也同样倍受关注。本文将瑞芬太民呼吸抑制的机理,特点,影响因素,及临床应用时与镇静药的协同作用进行综述。 Remifentanil is a new opioid with rapid onset and offset resulting from its unique chemical structure. It has been widely used in the fields of anesthesia and analgesia, but much impertence was atteched to the adverse effect of respiratory depression, This article reviewed the mechanism, characteristics, influencing factor, and interaction with other sedatives on this effect of remifentanil
作者 董佳 王保国
出处 《麻醉与监护论坛》 2006年第2期82-85,共4页 Forum of Anesthesia and Monitoring
关键词 瑞芬太尼 呼吸抑制 Remifentanil Respirafory depression
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  • 1张晓琴,蔡英敏,薛荣亮,赵莉.舒芬太尼在老年患者全麻诱导中对血液动力学的影响[J].临床麻醉学杂志,2005,21(8):525-526. 被引量:87
  • 2李煜,梁淑屏,张永福,刘文兴,金宇林,赖国忠,陈金海.舒芬太尼和丙泊酚联合用于无痛人工流产手术的可行性研究[J].实用医学杂志,2006,22(2):212-213. 被引量:30
  • 3刘秀芬,吴新民.丙泊酚血浆靶控输注与不同镇痛药物用于人工流产术的麻醉效果[J].临床麻醉学杂志,2006,22(6):411-413. 被引量:24
  • 4王祥瑞.丙泊酚的剂量与镇痛和呼吸作用之间的关系.中华麻醉学杂志,2003,26(8):439-441.
  • 5Vuyk J. Clinical interpretation of pharmacokinetic and pharmacodynamic propofol-opioid interactions[J] .Acta Anaesthesiol Belg, 2001, 52 (4): 445.
  • 6Mi W, Sakai T, Kudo M, et al.The interaction between fentanyl and propofol during emergence from anesthesia: monitoring with the EEG - Bispectral index[J]. Clin Anaesth, 2003, 15 (2):103.
  • 7王勋力 廖家荣 李瑞钰 等.不同小剂量舒芬太尼与芬太尼辅助异丙芬用于无痛人流术的疗效比较[J].医药产业咨讯,2006,3:17-17.
  • 8Morton N, Johnson G, White M, et al. Propofol in paediatrie. Anaesth esia, 1992, 2 (1): 89
  • 9Vuyk J. Clinical interpretation of pharmacokinetic and pharmacodynamic propofol - opioid interactions. Acta Anaesthesiol Belg,2001,52 (4) :445
  • 10Mi W, Sakai T, Kudo M, et al. The interaction between fenfanyl and propofol during emergence from anesthesia: monitoring with the EEG - Bispectral index: J Clin Anesth, 2003, 15 (2) : 103

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