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胺碘酮与起搏器联合治疗病窦综合征并阵发性房颤的疗效观察

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摘要 目的:观察胺碘酮与起搏器联合治疗病窭综合征并阵发性房颤有效性及安全性。方法:对56例病窭综合征患者,起搏器治疗后仍有阵发性房颤(经心电图和动态心电图证实),在停用其他抗心律失常药物至少5个半衰期后按标准方案给予胺碘酮治疗。根据临床症状和动态心电图来评价疗效及安全性。结果:观察0.5~7年,显效31例(占55.4%),有效17例(占30.4%),总有效率为85.8%。在随访期间有1例TSH轻度升高,1例出现T3、T4升高.1例出现间质性肺炎。结论:胺碘酮与起搏器联合治疗病窦综合征并阵发性房颤疗效高、相对安全,但要注意早期发现和处理甲状腺和肺毒性作用。
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2006年第5期592-593,共2页 Chinese Journal of Hospital Pharmacy
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