摘要
AIM： To investigate the effect of firing noise on gastrointestinal transit and probe its mechanism by measuring the levels of plasma polypeptide hormones. METHODS： A total of 64 SD rats were randomly divided into a control group and three stimulating groups. Firing noise of different intensity by sub-machine guns was used as inflicting factor. The effect of firing noise on liquid substance gastrointestinal transit and solid substance gastrointestinal transit was observed by measuring the ratio of carbon powder suspension transmitting and barium sticks transmitting respectively. Plasma levels of polypeptide hormones were measured by radio-immunoassay. RESULTS： The noise accelerated gastrointestinal transit of solid food by more than 80 db;and accelerated gastrointestinal transit of liquid food significantly by more than 120 db. Meantime, plasma levels of plasma motilin （MTL）（157.47±16.08; 151.90±17.08）, somatostatin （SS）（513.97±88.77; 458.25±104.30）, substance P （SP）（115.52±20.70; 110.28±19.96） and vasoactive intestinal peptide （VIP） （214.21±63.17; 251.76±97.24） remarkably changed also. CONCLUSION： Within a certain intensity range, the firing noise changes the levels of rat plasma gastrointestinal hormones, but the gastrointestinal transit is still normal. Beyond the range, the noise induces plasma hormone levels disturbance and gastrointestinal transit disorder. ~
瞄准：调查在胃肠的运输上发射噪音的效果并且由测量血浆多肽荷尔蒙的层次探查它的机制。方法：64 只 SD 老鼠的一个总数随机被划分成一个控制组和三刺激组。由亚机器枪的不同紧张的开火的噪音被用作造成因素。在液体物质上发射噪音的效果胃肠的运输和稳固的物质胃肠的运输被测量碳粉末暂停播送和分别地播送的钡棍子的比率观察。多肽荷尔蒙的血浆层次被放射性免疫测定测量。结果：噪音由超过 80 db 加速了稳固的食物的胃肠的运输；并且由超过 120 db 显著地加速了液体食物的胃肠的运输。同时，血浆 motilin (MTL ) 的血浆层次(157.47+/-16.08；151.90+/-17.08 ) ， somatostatin (SS )(513.97+/-88.77；458.25+/-104.30 ) ，物质 P (SP )(115.52+/-20.70；110.28+/-19.96 ) 并且血管作用的肠的肽(贵宾)(214.21+/-63.17；251.76+/-97.24 ) 显著地也变化了。结论：在某个紧张范围以内，开火的噪音改变老鼠血浆胃肠激素的层次，但是胃肠的运输仍然是正常的。在范围以外，噪音导致血浆荷尔蒙层次骚乱和胃肠的运输混乱。
