摘要
本文用乙肝疫苗与小剂量干扰素等药物配伍治疗慢性乙肝及慢性病毒携带者。经一个疗程后,干扰素组、胎盘肽组和乙肝疫苗组HBsAg转阴率分别为13.7％,5.9％和0％;HBeAg转换率分别为68.8％,72.7％和20％。表明干扰素和免疫增强剂配伍对乙肝病毒复制有一定抑制作用,促使HBeAg转换,但对清除HBsAg无效。
In this paper chronic hepatitis B and its virus carriers were treated with HB Vaccine and small doses of interferon and thymosin. After one course of interferon group, placenta peptide group and HB-Vaccine group, the negative percentage of HBsAg were 13.7%, 5.9% and 0%, respectively. The changes of HBeAg were 68.8%, 72.7% and 20%, respectively. The results showed that combination of interferon and immunologic stimulant can control the replication of Hepatitis B Virus, and impel HBeAg to change, but can not clear away HBsAg.
出处
《病毒学杂志》
CSCD
1990年第4期379-383,共5页
关键词
乙型肝炎
乙肝疫苗
干扰素
胸腺素
HB-Vaccine
α-interferon
Thymosin
Placenta peptide
Hepatitis B
