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老年人骨科手术使用腰-硬联合麻醉对肾素-血管紧张素系统的影响 被引量:3

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摘要 目的观察腰-硬联合麻醉对老年股骨上段手术病人肾素-血管紧张素(RAS)的影响.方法40例ASAⅠ~Ⅲ级老年择期手术病人,随机分为硬膜外麻醉组(EA组,n=20)和腰-硬联合麻醉组(CSEA组,n=20).分别记录麻醉前(T0)、麻醉后15 mIn(T1)、开刀时(T2)、使用骨水泥10min(T3)、术毕(T4)时平均动脉压(MAP)、心率(HR)、血氧饱和度(SpO2)、肾素(PRA)及血管紧张素Ⅱ(AngⅡ)的变化.记录痛觉阻滞平面达T10水平的时间.结果两组病人在T0时MAP、HR、SpO2、PRA、AngⅡ值差异不显著(P>0.05).同EA组相比,CSEA组麻醉起效时间明显缩短(P<0.05),两组MAP在T1、T2、T3各时点值均比T0值明显降低(P<0.05).CSEA组PRA、AngⅡ的T1、T2、T3值比T0值明显减少(P<0.05).在T2、T3时PRA、AngⅡ值两组间比较差异显著(P<0.05).HR及SpO2值在组内及组间比较差异均不显著(P>0.05).结论腰-硬联合麻醉用于老年股骨上段手术,只要运用得当,不会对老年人产生不利影响.
出处 《中国老年学杂志》 CAS CSCD 北大核心 2006年第4期476-477,共2页 Chinese Journal of Gerontology
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  • 1Meersschaert K, Brun L, Gourdin M, et al. Terllpressin-ephedrine versus ephedrine to treat hypotension at the induction of anesthesia in patients chronically treated with angiotens in converting-enzyme inhibitors: a prospective, randomized, double-blinded
  • 2Van Kesteren CA, Saris JJ, Dekkers DH, et al. Cultured neonatal rat cardiac myocytes and fibroblasts do not synthesize renin or angiotensinogen:evidence for stretch-induced cardiomyocyte hypertrophy independent of angiotensin Ⅱ. Cardiovasc Res, 1999,43(1
  • 3Petropoulos G, Vadalouca A, Siafaka I, et al. Renin-aldosterone system alterations during abdominal gynaecological operations under general or combined general and epidural anaesthesia. Clin Exp Obstet Gynecol,2000,27(1):42-46.
  • 4Evans RG, Correia AG, Weekes SR, et al. Responses of regional kidney perfusion to vasoconstrictors in anaesthetized rabbits: dependence on agent and renal artery pressure. Clin Exp Pharmacol Physiol, 2000, 27 (12):1007-1012.
  • 5Brabant SM, Bertrand M, Eyraud D, et al. The hemodynamic effects of anesthetic induction in vascular surgical patients chronically treated with angiotensin Ⅱ receptor antagonists. Anesth Analg, 1999 , 89(6): 1388-1392.
  • 6Picker O, Schwarte LA, Roth HJ, et al. Comparison of the role of endothelin, vasopressin and angiotensin in arterial pressure regulation during sevotlurane anaesthesia in dogs. Br J Anaesth,2004,92(1): 102-108.
  • 7Burnier M.Angiotensin Ⅱ type 1 receptor blockers. Circulation,2001,103(6) :904-912.
  • 8De Mello WC, Danser AH. Angiotensin Ⅱ and the heart: on the intracrine renin-angiotensin system. Hypertension,2000,35(6): 1183-1188.
  • 9Schieffer B, Paxton WG, Marrero MB, et al. Importance of tyrosine phosphorylation in angiotensin Ⅱ type 1 receptor signaling. Hypertension, 1996,27(3 Pt 2):476-480.
  • 10Lasocki S, Provenchere S, Benessiano J, et al. Cardiac troponin I is an independent predictor of in-hospital death after adult cardiac surgery. Anesthesiology, 2002,97 ( 2 ) :405-411.

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