摘要
目的:通过对急性胰腺炎(AP)发病过程中血清IL-8、IL-10、血Ca2+含量变化,分析其变化规律,判断病情的发展及变化。方法应用ELISA法测定,对52例AP及30例健康对照组(NS)IL-8、IL-10、血Ca2+的水平比较。结果AP患者血清IL-8I、L-10水平明显高于NS组(P<0.05),在发病第1天,重症胰腺炎(SAP)与轻症胰腺炎(MAP)血清Ca2+水平明显降低,而在AP病程中、后期无明显差异。结论IL-8I、L-10参与了AP发生发展过程,且IL-8、IL-10、血Ca2+水平可以作为AP病情轻重及转归的指标。
Objective To study the changes and significance of serum levels of interleukin - 8 and interleukin - 10 and Ca^2＋ in patients with acute pancreatitis（AP）. Method The serum levels of IL - 8, IL - 10 and Ca^2＋ in 52 AP patients were assayed by ELISA and compared with those in 30 normal salbjects（NS）. Results The levels of serum IL- 8, IL- 10 in AP patients were significantly higher than those in NS （ P 〈 0.05）. The level of serum Ca^2＋ in severe AP patients on the day of AP onset was lower than those in mild AP patients and NS （ P 〈 0.05 ）, whereas there was no significant difference in the intermediate and late stages of morbid course. （ P 〉 0.05）. Conclusions The serum levels of IL - 8 and IL- 10 are related to the development of acute panreatitis; so they can serve as an indicator of the development of acute panereatitis.
出处
《武警医学》
CAS
2006年第4期279-281,共3页
Medical Journal of the Chinese People's Armed Police Force
