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关于酸、碱平衡调节中肺作用的数学描述 被引量:2

Mathematical Description about Lung Function in the Adjustment of Acid-base Balance
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摘要 在正常或疾病情况下,人体内酸碱平衡的调节是一个颇为复杂的过程.迄今尚存很多争议性问题,近年国外多倾向于建立各种数学模型,以期揭示体内酸碱平衡的调节机制.本文将“顺应性”这一概念,引入到人体酸碱平衡调节的研究中,并观察了在代谢性酸中毒和代谢性碱中毒时,肺参与代偿调节的顺应性变化范围和变化幅度,为应用数学模型进一步深入探讨机体内复杂的酸碱平衡调节机制,提供新的研究途径和手段. Abstract: Regulation of acid-base balance in human body is a quite complicated process in normal or disease case. There is a lot of disputed questions up to now. It is a tendency to build all kinds of mathematical model abroad newly so as to reveal adjusted mechanism of acid-base balance in human body. The conception of 'acclimation property' was introduced to the study of acid-base balance in human body in the thesis. And changed scope and range of acclimation property about lung participating in compensatory adjustment were observed in acid-base balance. It provides a new research ways and means for more further discussing deeply complicated adjusted mechanism of acid-base balance in human body.
出处 《数学的实践与认识》 CSCD 北大核心 2006年第4期106-113,共8页 Mathematics in Practice and Theory
基金 辽宁省教育厅资助项目(05L507)
关键词 酸碱平衡 肺调节 数学描述 顺应性 acid-base balance regulation of lung mathematical description compliance
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参考文献4

  • 1James Duffin. The role of acid-base balance in the chemoreflex control of breathing[J]. J Appl Physiol August 18,2005.
  • 2Horatio J Adrogue, Nicolaos E. Madias: PCO2 and [K^+] p in metabolic acidosis: certainty for the first and uncertainty for the other[J]. J Am Soc Nephrol, 2004, 15: 1667-1668.
  • 3John A Kellum. Determinants of blood pH in health and disease[J]. Critical Care, 2000, 4: 6-14.
  • 4Bernhard M Schmitt. The quantitation of buffering action II. Applications of the formal & general approach[J].Theor Biol Med Model, 2005, 2: 9.

同被引文献8

  • 1James Duffin.The role of acid-base balance in the chemoreflex control of breathing[J].J Appl Physiol August 18.2005.286.
  • 2Horacio J Adrogue,Nicolaos E Madias.PCO2 and[K^+]p in metabolic acidosis:Certainty for the first and uncertainty for the other[J].J Am Soc Nephrol,2004,15:1667-1668.
  • 3John A Kellum.Determinants of blood pH in health and disease[J].Critical Care,2000,4:6-14.
  • 4Bernhard M Schmitt.The quantitation of buffering action Ⅱ.Applications of the formal & general approach[J].Theor Biol Med Model,2005,2:9.
  • 5James Duffin.The role of acid-base balance in the chemoreflex control of breathing[J].J Appl Physiol August,2005,18:568-570.
  • 6Horacio J Adrogue,Nicolaos E Madias.PCO2 and[K+]p in metabolic acidosis:Certainty for the first and uncertainty for the other[J].J Am Soc Nephrol,2004,15:1667-1668.
  • 7John A Kellum.Determinants of blood pH in health and disease[J].Critical Care 2000,4:6-14.
  • 8Bernhard M Schmitt.The quantitation of buffering action Ⅱ.Applications of the formal & general approach[J].Theor Biol Med Model,2005,2:9-10.

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