摘要
目的了解慢性前列腺炎(CP)与病原菌的关系以及病原菌的耐药状况。方法对门诊274例CP患者进行前列腺液(EPS)细菌培养并进行菌种鉴定和耐药性测试,结果根据NCCLS规定进行判断。结果在274份标本中,107例(39．1%)培养呈阳性,G^+菌占92．5%(99/107),G^-菌占7．5%(8/107)。其中金黄色葡萄球菌88株,占82．24%(88/107),远远高于其它菌种,检出耐甲氧西林金黄色葡萄球菌(MRSA)30株,占金黄色葡萄球菌的34．1%。MRSA对青霉素、苯唑西林、克林霉素、阿奇霉素、环丙沙星、庆大霉素,四环素的耐药率显著高于甲氧西林敏感金黄色葡萄球菌(MSSA)。没有发现耐万古霉素菌株。结论CP患者前列腺液中分离出的细菌以金黄色葡萄球菌为主,MRSA占相当高比例,呈多重耐药。在CP的治疗过程中要严格掌握抗生素使用指征,避免滥用抗生素。
Objective To investigate the relationship between chronic prostatitis（CP） and the pathogenic bacteria,and antibiotic resistance of bacteria from patients with CP. Methods A total of 274 patients with CP underwent test of midstream urine culture, leukocyte counting of expressed prostate secretion（EPS）, EPS / post prostatic massage urine（PPMU） culture, and the susceptibilities of the bacteria were detected. Results A total of 107 strains （39.1 %） of bacteria were isolated from 274 EPS specimens, 82.2% （88/107） of which were Staphylococcus aureus and the rate of Meticillin resistant Staphylococcus aureus （MRSA） was 34. 1%（30/88）.The drug resistance rate of MRSA, to penicillin, oxacillim, clindamycin, azithromycin, ciproflaxaci, gentamycin and tetracycline was higher significantly than Meticillin sensitive Staphylococcus aureus （MSSA）, and all MRSA was sensitive to vancomycin. Conclusion The chief pathogenic bacteria is Staphylococcus aureus and MRSA is common, which is meticillinresistant; We should hold firmly the principle as give antibiotic to patients with CP and avoid drug abuse.
出处
《中国男科学杂志》
CAS
CSCD
2006年第4期20-22,34,共4页
Chinese Journal of Andrology
基金
国家自然科学基金资助(编号:30471724)
