摘要
目的:探讨附有碘-125粒子的医用记忆合金食管支架置入对晚期食管恶性狭窄的疗效．方法:45例晚期食管癌按患者是否愿意接受碘-125粒子支架而将其分为A、B两组,A组为普通自膨式支架,B组为附有碘-125粒子的自膨式食管支架进行治疗．术后随访并发症及生存期．结果:45例患者支架全部顺利置放,支架置入成功率100％,患者吞咽困难均得到明显缓解． A组患者生存时间90-300 d,平均171±56 d．B 组患者生存时间120-450 d,平均316±116 d．两者比较有统计学意义(t=-3．385,P<0．05)．两组均未出现严重并发症．结论:附有碘-125粒子的自膨式食管支架能明显缓解吞咽困难症状,明显提高患者生活质量及生存期,且无严重并发症发生．
AIM： To analyze the curative effect of self-expandable medical memorial metallic stent with iodine-125 seeds in the treatment of esophageal carcinoma at advanced Stage.
METHODS： Forty-five patients with esophageal carcinoma at advanced stage were divided into group A and B, The patients in group A were treated with normal self-expandable stents, while those in group B received the stents with iodine-125 seeds, After the operation, the patients were followed up and their complications and survival time were analyzed.
RESULTS： The stents were successfully implanted in all the 45 patients. The patients were obviously relieved from their difficulties in swallowing, The survival time of patients in group A were 90-300 d, with an average of 171 ± 56 d, and those in group B were 120-450 d, with an average of 316 ± 116 d. There was significant difference between them （t = -3.385, P 〈 0.05）. CONCLUSION： Self-expandable stent with iodine-125 seeds can obviously alleviate the symptoms of difficulty in swallowing, improve the patients＇ life quality and survival time.
出处
《世界华人消化杂志》
CAS
北大核心
2006年第8期814-818,共5页
World Chinese Journal of Digestology
基金
甘肃省中青基金资助课题
No.YS-011-A23-20
