摘要
直肠癌是常见的消化道恶性肿瘤,手术是直肠癌的主要治疗手段,放化疗对可手术直肠癌是重要的辅助治疗手段。无论术前或术后放疗均可提高局部控制,术前放疗可增加保肛的机率,放疗的方式以常规分割较佳。术后放疗在中度复发危险的患者中对生存的影响与化疗相似,但需要两者对局控的资料。本文综述的是术前放疗、术后放疗以及术前与术后放疗的比较。
Rectal cancer is a common malignant tumor in the gastrointestinal system. For the patients with resectable but high-rlsk rectal cancer, neoadjuvant and adjuvant chemoradiation plus surgery may improve local control. Compared to adjuvant chemnradiatinn, neoadjuvant ehemoradiation showed the advantage of sphincter preservation. When the goal of preoperative chemoradiation was sphincter preservation, conventional radiotherapy was recommended. Through the analysis of the patients with 5-year survivals, the radiation had a similar impact on the survival as the chemotherapy alone for the patients with the intermediate risk factors. The impact on local control need to be further investigated before recommending chemotherapy alone for those subset patients. Advances in preoperative irradiation, postoperative irradiation and the comparison of preoperative irradiation with postoperative irradiation are also reviewed in this article.
出处
《中国癌症杂志》
CAS
CSCD
2006年第5期399-402,404,共5页
China Oncology
关键词
直肠癌
手术
术后放疗
术前放疗
放化疗
rectal cancer
surgery
postoperative radiation
preoperative radiation
chemoradiation
