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Self-expandable metallic stents for malignant biliary obstruction:Efficacy on proximal and distal tumors 被引量:12

Self-expandable metallic stents for malignant biliary obstruction:Efficacy on proximal and distal tumors
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摘要 AIM: To compare the efficacy of self-expandable metallic stents (EMS) in the treatment of distal and proximal stricture of malignant biliary tumors. METHODS: From March 1995 to June 2004, 61 patients (40 males, 21 females) with malignant biliary obstruction who received self-expandable metallic stent implantation were reviewed retrospectively. The stents were inserted by an endoscopic or percutaneous transhepatic method. We tried to place two stents in the biliary system in T or Y configuration in cases of hilar tumors with bilateral hepatic duct obstruction. The end points of the study were stent occlusion or patient death. RESULTS: The mean time of stent patency was 421 ± 67 d in the group of proximal stricture( group Ⅰ) and 168 ± 18 d in the group of distal stricture (group Ⅱ). The difference was significant in borderline between the two groups (P = 0.0567). The mean survival time was 574 ± 76 d in group I and 182 ± 25 d in group II. There was a significant difference between the two groups (P = 0.0005). CONCLUSION: EMS implantation is a feasible, palliative method for unresectable malignant biliary obstruction. The clinical efficacy of EMS in patients with proximal hilar tumors is better than that in patients with distal tumors. 瞄准:在恶意的胆汁的肿瘤的远侧、近似的苛评的治疗比较自我可扩充的金属性的 stents (他们) 的功效。方法:从 1995 年 3 月到 2004 年 6 月, 61 个病人(40 男性, 21 女性) 与恶意的胆汁的阻塞,收到了自我可扩充的金属性的斯滕特氏印模膏培植的人,回顾地被考察。stents 被一个内视镜或经皮的 transhepatic 方法插入。我们试着在门肿瘤的情况下在 T 或 Y 配置把二 stents 交给在胆汁的系统双边的肝的管阻塞。学习的终点是斯滕特氏印模膏吸藏或耐心的死亡。结果:斯滕特氏印模膏明显的吝啬的时间是 421 +/- 在近似苛评的组的 67 d (组我) 并且 168 +/- 在远侧的苛评(组 II ) 的组的 18 d。差别在在二个组之间的边线是重要的(P = 0.0567 ) 。吝啬的生存时间是 574 +/- 在组的 76 d 我和 182 +/- 在组 II 的 25 d。在二个组之间有有效差量(P = 0.0005 ) 。结论:他们培植是为 unresectable 的一个可行、辩解的方法恶意的胆汁的阻塞。在有近似的门肿瘤的病人的他们的临床的功效在有远侧的肿瘤的病人比那好。
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第1期119-122,共4页 世界胃肠病学杂志(英文版)
关键词 Metallic stent Biliary malignancy 可扩张金属 胆汁阻塞 病理机制 治疗
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参考文献16

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