1Hoff PM;Ansari R;Batist G.Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer:results of a randomized phase Ⅲ study,2001(08).
2Twelves C;Wong A;Nowacki MP.Capecitabine as adjuvant treatment for stage Ⅲ colon cancer[J],2005(26).
3Meropol NJ.Oral fluoropyrimidines in the treatment of colorectal cancer[J],1998(10).
4Sobrero A;Guglielmi A;Grossi F.Mechanism of action of fluoropyrimidines:relevance to the new developments in colorectal cancer chemotherapy,2000(zk).
5Lokich JJ;Ahlgren JD;Gullo JJ.A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma:a Mid-Atlantic Oncology Program Study,1989(04).
6Andre T;Colin P;Louvet C.Semimonthly versus monthly regimen of fluorouracil and leucovorin administered for 24 or 36 weeks as adjuvant therapy in stage II and III colon cancer:results of a randomized trial[J],2003(15).
7Weh HJ;Wilke HJ;Dierlamm J.Weekly therapy with folinic acid (FA) and high-dose 5-fluorouracil (5-FU) 24-hour infusion in pretreated patients with metastatic colorectal carcinoma.A multicenter study by the Association of Medical Oncology of the German Cancer Society (AIO),1994(03).
8de Gramont A;Bosset JF;Milan C.Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer:a French intergroup study[J],1997(02).
9Petrelli N;Herrera L;Rustum Y.A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma,1987(10).
10O'Connell MJ;Mailliard JA;Kahn MJ.Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer[J],1997(01).
2Zheng S. Recent study on coloreetal cancer in China: early detection and novel related gene[J]. Chin Med J (Engl), 1997, 110(4): 309 - 310.
3Lawrence W Jr, Terz JJ, Horsley S 3rd, et al. Chemotherapy as an adjuvant to surgery for colorectal cancer[ J]. Ann Surg, 1975, 181 (5) :616 -623.
4Rothenberg ML. Current status of capecitabine in the treatment of colorectal cancer [ J ]. Oncology ( Williston Park ), 2002, 16 ( 12 Suppl No 14) : 16 -22.
5Hoff PM, Ansari R, Batist G, et al. Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase Ⅲ study[J]. J Clin Oncol, 2001, 19(8) : 2282 - 2292.
6Twelves C, Wong A, Nowacki MP, et al. Capecitabin adjuvant treatment for stage Ⅲ colon cancer [ J ]. N Engl J Med, 2005,352 ( 26 ) :2696 - 2704.
7Harms BA, Gracbow L, Niederbuber JE, et al. Colon and rectum [ M ]//Abeloff MD, Armitage JO, Lichter, et al. Clinical oncology. 2nd. Singapore: Harcourt Asia Churchill Livingstone, 2001, 1646.
8Halling KC, French A J, McDonnell SK, et al. Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers [J]. J Nail Cancer Inst, 1999, 91(15) : 1295 -1303.
9Bismuth H, Adam R, Levi F, et al. Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy [J]. Ann Surg, 1996, 224(4) :509 -522.
10Andre T, Boni C, Mounedji-Boudiaf L, et al. Oxaliplatin, fluorouracil, and leueovofin as adjuvant treatment for colon cancer[ J]. N Eng J Med, 2004, 350(23):2343-2351.