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结直肠癌辅助化疗演进及新进展 被引量:1

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摘要 5-氟脲嘧啶作为结直肠癌辅助化疗的基础药物已有40余年历史,不同给药途径及方式可以影响结肠癌化疗疗效。奥沙利铂、卡培他滨等新化疗药物治疗结直肠癌疗效逐步得到肯定。血管内皮生长因子受体抑制剂、表皮生长因子受体抑制剂等分子靶向药物也正进入临床研究。本文将对5-FU、新一代化疗药物以及分子靶向药物在结肠癌辅助化疗中的演进及新进展作一综述。
出处 《实用医技杂志》 2006年第6期962-964,共3页 Journal of Practical Medical Techniques
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  • 1Hoff PM;Ansari R;Batist G.Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer:results of a randomized phase Ⅲ study,2001(08).
  • 2Twelves C;Wong A;Nowacki MP.Capecitabine as adjuvant treatment for stage Ⅲ colon cancer[J],2005(26).
  • 3Meropol NJ.Oral fluoropyrimidines in the treatment of colorectal cancer[J],1998(10).
  • 4Sobrero A;Guglielmi A;Grossi F.Mechanism of action of fluoropyrimidines:relevance to the new developments in colorectal cancer chemotherapy,2000(zk).
  • 5Lokich JJ;Ahlgren JD;Gullo JJ.A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma:a Mid-Atlantic Oncology Program Study,1989(04).
  • 6Andre T;Colin P;Louvet C.Semimonthly versus monthly regimen of fluorouracil and leucovorin administered for 24 or 36 weeks as adjuvant therapy in stage II and III colon cancer:results of a randomized trial[J],2003(15).
  • 7Weh HJ;Wilke HJ;Dierlamm J.Weekly therapy with folinic acid (FA) and high-dose 5-fluorouracil (5-FU) 24-hour infusion in pretreated patients with metastatic colorectal carcinoma.A multicenter study by the Association of Medical Oncology of the German Cancer Society (AIO),1994(03).
  • 8de Gramont A;Bosset JF;Milan C.Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer:a French intergroup study[J],1997(02).
  • 9Petrelli N;Herrera L;Rustum Y.A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma,1987(10).
  • 10O'Connell MJ;Mailliard JA;Kahn MJ.Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer[J],1997(01).

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  • 1林国乐,邱辉忠.结直肠癌辅助化疗的新观念和新进展[J].癌症进展,2005,3(2):139-143. 被引量:15
  • 2Zheng S. Recent study on coloreetal cancer in China: early detection and novel related gene[J]. Chin Med J (Engl), 1997, 110(4): 309 - 310.
  • 3Lawrence W Jr, Terz JJ, Horsley S 3rd, et al. Chemotherapy as an adjuvant to surgery for colorectal cancer[ J]. Ann Surg, 1975, 181 (5) :616 -623.
  • 4Rothenberg ML. Current status of capecitabine in the treatment of colorectal cancer [ J ]. Oncology ( Williston Park ), 2002, 16 ( 12 Suppl No 14) : 16 -22.
  • 5Hoff PM, Ansari R, Batist G, et al. Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase Ⅲ study[J]. J Clin Oncol, 2001, 19(8) : 2282 - 2292.
  • 6Twelves C, Wong A, Nowacki MP, et al. Capecitabin adjuvant treatment for stage Ⅲ colon cancer [ J ]. N Engl J Med, 2005,352 ( 26 ) :2696 - 2704.
  • 7Harms BA, Gracbow L, Niederbuber JE, et al. Colon and rectum [ M ]//Abeloff MD, Armitage JO, Lichter, et al. Clinical oncology. 2nd. Singapore: Harcourt Asia Churchill Livingstone, 2001, 1646.
  • 8Halling KC, French A J, McDonnell SK, et al. Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers [J]. J Nail Cancer Inst, 1999, 91(15) : 1295 -1303.
  • 9Bismuth H, Adam R, Levi F, et al. Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy [J]. Ann Surg, 1996, 224(4) :509 -522.
  • 10Andre T, Boni C, Mounedji-Boudiaf L, et al. Oxaliplatin, fluorouracil, and leueovofin as adjuvant treatment for colon cancer[ J]. N Eng J Med, 2004, 350(23):2343-2351.

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