摘要
利用差分方法对电渗驱动微通道中的脉冲样品的浓度扩散进行了数值模拟,结果说明外加电场和缓冲液浓度对样品的扩散起着重要的作用,而水力直径及其通道的高宽比对扩散的影响甚微.采用减小外加电场和减小缓冲液浓度的办法,可以防止样品带宽的增大、增强检测和分离的效果,同时又保持比较快的输送速度.该结论对于微通道的优化设计具有参考价值.
Numerical simulation using the finite differential method was carried out to analyze the diffusion of an impulse sample in the micro-channel driven by electroosinosis. The results show that the electrical field strength applied externally and the concentration of buffer solution played a significant role in the diffusion of sample, however, hydraulic diameter and aspect ratio of height to width of channel played a small role in it. Weakening the electrical field strength applied externally and the concentration of buffer solution properly could prevent the sample band from broadening effectively, and pronted the efficiency of testing and separation as well as kept a faster speed of transport. The conclusions were helpful to the optimal design for micro-channel.
出处
《应用数学和力学》
CSCD
北大核心
2006年第5期512-518,共7页
Applied Mathematics and Mechanics
基金
国家自然科学基金(重大)资助项目(20299030)
关键词
微通道
扩散
电渗驱动
数值计算
micro-channel
diffusion
driven by electroosmosis
numerical simulation
