摘要
本文应用P53蛋白单克隆抗体,检测42例甲状腺瘤及36例甲状腺癌。结果发现,相当数量甲状腺癌和甲状腺腺瘤有P53蛋白表达。阳性产物定位于癌细胞核。揭示突变型P53蛋白与甲状腺肿瘤发生、发展及预后有关。
42 cases of thyroid adenomas and 36cases of thyroid carcinomas were immunohistochemically stained using P53 protein monoclonal antibody. Many thyroid carcinomas expressed P53 as a positive nucleus staining. The results indicate that the expression of mutant P53 in thyroid neoplasms is associated with tumor genesis, growth and prognosis.
出处
《交通医学》
1996年第2期4-5,共2页
Medical Journal of Communications
