摘要
目的研究促肾上腺皮质激素释放激素(corticotrop in-releasing hormone,CRH)对大鼠腹腔巨噬细胞吞噬功能的影响。方法灌洗提取大鼠腹腔巨噬细胞,加CRH培养1、2、4、8、16小时后加鸡红细胞,根据巨噬细胞吞噬鸡红细胞指数和吞噬率,评定CRH对大鼠腹腔巨噬细胞吞噬功能的影响。结果实验组各时相组吞噬率及吞噬指数与对照组比较均明显增高(P<0.05),实验组各时间组之间比较,2小时组有一个吞噬高峰,吞噬率及吞噬指数均为最高数值。结论CRH能明显提高大鼠腹腔巨噬细胞的吞噬能力。
Objective To explore the effect of corticotropin-releasing hormone （ CRH ） on phagocytosis of rat enterocoelia macrophage. Methods The chicken-red cells were added in the media of rat enterocoelia macrophage cultivated by CRH after 1.2.4.8.16 hours. Then the effect of CRH on phagocytosis of rat enterocoelia macrophage was evaluated by the chicken-red cells phagocytosis index and phagocytosis rate. Results Comparing with the control groups, the phagocytosis index and phagocytosis rate of experimental groups both improved significantly in each time point （P 〈 0.05 ）. Among the experimental groups, the phagocytosis index and phagocytosis rate were the highest and the phagocytosis was at the top in the 2 hours group. Conclusion CRH could markedly improve the phagocytosis of rat enterocoelia macrophage.
出处
《创伤外科杂志》
2006年第1期59-62,共4页
Journal of Traumatic Surgery
基金
"973"创伤项目第一分题(1999054201)
