RNAi下调β分泌酶表达治疗阿尔茨海默病的前景展望
摘要
β淀粉样蛋白沉积是多种因素导致阿尔茨海默病发病的共同通路。本文介绍了近年来在β淀粉样蛋白及其相关的β分泌酶在阿尔茨海默病发病机制作用研究中所取得的进展,并对利用RNA干扰技术下调β分泌酶表达治疗阿尔茨海默病的进展及前景作一综述,以期为治疗阿尔茨海默病的药物研发提供思路。
出处
《国际神经病学神经外科学杂志》
2006年第2期142-145,共4页
Journal of International Neurology and Neurosurgery
基金
国家自然科学基金(30572081)
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