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急性缺血性脑梗塞患者脑脊液中β2微球蛋白含量的变化 被引量:3

Change of β 2 microglobulin in cerebrospinal fluid in acute ischemic cerebral infarction
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摘要 测定44例急性缺血性脑梗塞(AICI)患者和24例正常对照者脑脊液(CSF)β2微球蛋白(β2MG)的含量。结果:AICI组CSFβ2MG的含量(1.50±0.38mg/L)明显高于正常组(1.14±0.32mg/L);8例严重偏瘫的大片梗塞患者CSFβ2MG含量升高更著(1.91±0.34mg/L);AICI组中20例患者治疗后CSFβ2MG含量(1.18±0.30mg/L)明显低于治疗前(1.46±0.39mg/L)。作者推测AICI患者CSFβ2MG含量升高可能与中枢神经系统内发生免疫反应有关。 ? 2 microglobulin(β 2MG) contents in cerebrospinal fluid(CSF) were determined in 44 patients with acute ischemic cerebral infarction(AICI) and compared with 24 normal controls.The results showed that CSF β 2MG contents in AICI were singificantly higher than those of the controls.CSF β 2MG levels were much higher in 8 patients with serious hemiplegia and massive infarction.In 20 cases,the contents after treatment were markedly lower than those before treatment.It was surminsed that tne elevation of CSFβ 2 MG levels in AICI might be related to the immunological response within the central nervous system after acute brain tissue damage.
作者 张忠 肖林娅
出处 《中国危重病急救医学》 CAS CSCD 1996年第2期75-76,共2页 Chinese Critical Care Medicine
关键词 脑梗塞 β2微球蛋 白脑脊液 cerebral infarction β 2 microglobulin cerebrospinal fluid
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