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镁剂对急性心肌梗死再灌注损伤的影响

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摘要 目的评价急性心肌梗死早期镁剂治疗的临床疗效和安全性。方法对132例急性心肌梗死患者随机分为硫酸镁干预组(n=67)和对照组(n=65),干预组在接受溶栓前30分静脉给25%硫酸镁20ml,两组病人均接受静脉溶栓治疗,观察溶栓成功病例(镁剂治疗组n=39,对照组n=36)的心律失常、心肌酶、超声心动图负荷试验心肌顿抑的情况。结果与对照组比较,硫酸镁干预组室性心律失常发生较少(P<0.02),心肌酶峰值较低(P<0.001),梗死心肌和顿抑心肌节段较少(P<0.005),左室收缩功能优于对照组(P<0.05)。结论镁剂可以减少急性心肌梗死再灌注损伤,可作为急性心肌梗死的辅助治疗手段。
出处 《医学信息(西安上半月)》 2006年第4期654-656,共3页 Medical Information
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参考文献7

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