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156株铜绿假单胞菌的院内感染分布及耐药性调查 被引量:11

Distribution of Nosocomial Pseudomonas Aeruginosa Infection and Drug Resistance:Survey of 156 Strains
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摘要 目的:了解我院2004年1月~2005年8月临床分离的铜绿假单胞菌株分布特征及耐药情况,为临床治疗提供参考。方法:将我院患者送检各类标本进行分离、培养,采用细菌生化常规法进行菌株鉴定,采用K-B纸片扩散法进行药敏试验。结果:分离出的156株铜绿假单胞菌主要采自痰(64.74%)和伤口脓液(创面)(22.44%);科室分布以神经外科、烧伤科和外科最多,分别占34.62%、21.79%、16.03%;其对包括头胞唑啉、呋喃妥因、复方新诺明等的多种抗菌药耐药。结论:抗铜绿假单胞菌的药物选择上要强调结合科室的药敏状况,并需要不断进行监测。 OBJECTIVE: To study the distribution characteristics and drug - resistance of the clinically isolated pseudomonas aeruginosa in our hospital from Jan.2004 to Aug.2005 for the reference of cllnlcs.METHODS: Different kinds of specimen for detection taken from the inpatients of our hospital were isolated and cultured,identification of strains was carried out by the conventional biochemical assay and susceptibility test was done by Kirby Bauer method .RESULT.Of the total 156 pseudomonas aeruginosa isolated, 64.74% were from the specimen of phlegm, followed by purulence surface of the wound at 22.44% ;In terms of its distribution in hospital departments,leading the list were neurosurgery,burn department and surgery, occupying 34.62%, 21.79% and 16.03%, respectively.Pseudomonas aeruginosa was resistant to many antibiotics like cefazolin, furadantin, bactrim, etc,CONCLUSION: The choice of anti- pseudomonas aeruginosa infection drugs should be based on its drug susceptibility, which should be under frequent monitoring.
出处 《中国药房》 CAS CSCD 北大核心 2006年第7期524-525,共2页 China Pharmacy
关键词 铜绿假单胞菌 院内感染 药物敏感性 Pseudomonas aeruginosa Nosocomial infection Drug susceptibility
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  • 1Itokazu GS, Quinn JP, Bell-Dixon C, et al. Antimicrobial resistance rates among aerobic gram-negative bacilli recovered from patients in intensive-care units: evaluation of a national postmarketing surveillance program. Clin Infect Dis, 1996, 23: 779-784.
  • 2Jarvis WR, Martone WJ. Predominant pathogens in hospital infections. J Antimicrob Chemother, 1992, 29(suppl A): 19-24.
  • 3Hilf M, Yu VL, Sharp J, et al. Antibiotic therapy for Psedomonas aeruginosa bacteriemia: outcome correlations in a prospective study of 200 patients. Am J Med, 1989, 87:540-546.
  • 4Lanson EL. Persistent carriage of gram-negative bacteria on hands. Am J Infect Control, 1981, 9: 112-119.
  • 5Urban C, Go E, Mariano N, et al. Effect of sulbactam on infections caused by imipenem-resistant Acinetobacter calcoaceticus biotype anitratus. J Infect Dis, 1993, 167: 448-451.
  • 6Ang SW, Lee ST. Emergence of a multiple-resistant strain of Acinetobacter in a bums unit. Ann Acad Med Singapore, 1992, 21:660-603.
  • 7Murray PR, Baron E J, Pfaller MA, et al. Manual of clinical laboratory.7th Edition. Washington DC: American Society for Microbiology, 1999,552-554.
  • 8Quinn JP. Clinical problem posed by multiresistant nonfermenting gramnegative pathogens. Clin Infect Dis, 1998, 27(Suppl 1 ): S117-124.
  • 9王辉,陈民钧,中国医院内病原菌耐药监测网.1994~2001年中国重症监护病房非发酵糖细菌的耐药变迁[J].中华医学杂志,2003,83(5):385-390. 被引量:422

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