摘要
目的为探讨尿胰蛋白酶原Ⅱ(Try-Ⅱ)对急性胰腺炎(AP)筛检与诊断价值,为AP的诊断提供一种微量、操作简单、快速,结果准确可靠的常规检测方法。方法选择急性胰腺炎40例为实验组,非急性胰腺炎(NAP)52例为对照组,分别用免疫层析法测尿中Try-Ⅱ,速率法测血、尿中的淀粉酶(Amy)。结果40例急性胰腺炎患者38例Try-Ⅱ为阳性,34例血Amy阳性,35例尿Amy阳性。尿Try-Ⅱ诊断灵敏度95%,特异性94.2%,诊断符合率94.5%。血Amy灵敏度85%,特异性80.7%,诊断符合率82.6%。尿Amy灵敏度88%,特异性79%,诊断符合率82.6%。结论尿Try-Ⅱ作为急性胰腺炎新的生化标志物,对急性胰腺炎的快速检测及疗效观察优于血、尿Amy,具有较高的诊断价值,是诊断AP的良好指标。
Objective To search the values of uvinary trysinogen-2 in screening and diagnosis of acute pancreatitis and to provide a rountine method which is microsample, simple procedure, short analysis time and accurate result for diagnosis of acute pancreatitis （AP） . Methods Uvineary trysinogen- Ⅱ （Try- Ⅱ ） was meassured with imrnnochromatograph in 40 cases of AP and 52 cases of non acute pancreatitis（NAP）, and compared with the serum amylase（AMS） and urine （AMU） were measured with rate method. Resalts The positive samples of uvinary Try- Ⅱ ,AMS,AMU were 38,34,35 respectively in 40 AP patients. The diagnostic sensitivity of uvinary Try-Ⅱ , AMS,AMU were 95 %,85 % and 88 % respectively. The specificity of uvinary Try-Ⅱ ,AMS, AMU were 94. 2% ,80.7% and 79% respectively while the diagnostic accuracy of uvinary Try- Ⅱ ,AMS,AMU were 94.5% ,82.6% and 82.6% respectively. Conclusion Urinary Try- Ⅱ is a new biochemical maker with short analysis time and monitoring of treatment is superior to AMS and AMU for AP. It has a good dignostic value for AP.
出处
《重庆医学》
CAS
CSCD
2006年第7期640-641,共2页
Chongqing medicine
